tert-butyl 3-methylideneazetidine-1-carboxylate
1-Boc-3-methylene-azetidine
CAS: 934664-41-2
Molecular Formula: C9H15NO2
tert-butyl 3-methylideneazetidine-1-carboxylate - Names and Identifiers
tert-butyl 3-methylideneazetidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C9H15NO2 |
| Molar Mass | 169.22 |
| Density | 1.02±0.1 g/cm3(Predicted) |
| Boling Point | 214.8±29.0 °C(Predicted) |
| Appearance | clear liquid |
| Color | Colorless to Almost colorless |
| pKa | -1.56±0.20(Predicted) |
| Storage Condition | 2-8°C |
tert-butyl 3-methylideneazetidine-1-carboxylate - Introduction
1-Boc-3-methylene-azetidine is an organic compound with the chemical formula C9H17NO2. It is a colorless liquid with a pungent odor at room temperature. The following is information about the properties, uses, preparation methods and safety of the compound:
Nature:
-Appearance: colorless liquid
-relative molecular mass: 171.24g/mol
-Melting point:-63°C
-Boiling Point: 163-165°C
-density: 0.996 g/cm ^ 3
-Refractive Index: 1.454
Use:
1-Boc-3-methylene-azetidine is a commonly used organic synthesis intermediate, which is widely used in drug synthesis and other fields. It can be used as a protecting group and a bonding ligand for the synthesis of complex organic molecular structures such as catalysts and drug molecules.
Method:
The synthesis of 1-Boc-3-methylene-azetidine is usually accomplished by the following steps:
1.1-chlorocyclobutane reacts with methylamine to generate 3-methylene azetidine.
2. The obtained product is reacted with N,N-dimethylformamide diacetate to generate 1-Boc-3-methylene-azetidine.
Safety Information:
1-Boc-3-methylene-azetidine is an irritating compound and direct contact with skin and eyes should be avoided. Wear appropriate protective gloves and glasses during use or handling. In addition, it should be operated in a well-ventilated area to avoid inhalation of its volatiles. When storing and handling, keep away from fire and oxidant.
Due to the nature and wide range of uses of 1-Boc-3-methylene-azetidine, it must be used under suitable laboratory conditions and follow relevant safety procedures.
Nature:
-Appearance: colorless liquid
-relative molecular mass: 171.24g/mol
-Melting point:-63°C
-Boiling Point: 163-165°C
-density: 0.996 g/cm ^ 3
-Refractive Index: 1.454
Use:
1-Boc-3-methylene-azetidine is a commonly used organic synthesis intermediate, which is widely used in drug synthesis and other fields. It can be used as a protecting group and a bonding ligand for the synthesis of complex organic molecular structures such as catalysts and drug molecules.
Method:
The synthesis of 1-Boc-3-methylene-azetidine is usually accomplished by the following steps:
1.1-chlorocyclobutane reacts with methylamine to generate 3-methylene azetidine.
2. The obtained product is reacted with N,N-dimethylformamide diacetate to generate 1-Boc-3-methylene-azetidine.
Safety Information:
1-Boc-3-methylene-azetidine is an irritating compound and direct contact with skin and eyes should be avoided. Wear appropriate protective gloves and glasses during use or handling. In addition, it should be operated in a well-ventilated area to avoid inhalation of its volatiles. When storing and handling, keep away from fire and oxidant.
Due to the nature and wide range of uses of 1-Boc-3-methylene-azetidine, it must be used under suitable laboratory conditions and follow relevant safety procedures.
Last Update：2024-04-09 21:04:16
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Product Name: 1-Boc-3-methylideneazetid... Visit Supplier Webpage Request for quotation
CAS: 934664-41-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 934664-41-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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